20 results found for: “nucleocapsid”.

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Capsid

viral coat proteins (VCP). The capsid and inner genome is called the nucleocapsid. Capsids are broadly classified according to their structure. The majority...

Last Update: 2024-03-08T07:41:49Z Word Count : 2552 Synonim Capsid

Virus

association of viral capsid proteins with viral nucleic acid is called a nucleocapsid. The capsid and entire virus structure can be mechanically (physically)...

Last Update: 2024-02-19T07:41:10Z Word Count : 18118 Synonim Virus

Coronavirus nucleocapsid protein

The nucleocapsid (N) protein is a protein that packages the positive-sense RNA genome of coronaviruses to form ribonucleoprotein structures enclosed within...

Last Update: 2024-02-18T22:51:14Z Word Count : 2547 Synonim Coronavirus nucleocapsid protein

Human parainfluenza viruses

linked by di-sulphide bonds. Once complete, this is followed by the HPIV nucleocapsid entering the cytoplasm of the cell. Subsequently, genomic transcription...

Last Update: 2024-03-25T18:05:09Z Word Count : 2835 Synonim Human parainfluenza viruses

Coronavirus

enveloped viruses with a positive-sense single-stranded RNA genome and a nucleocapsid of helical symmetry. The genome size of coronaviruses ranges from approximately...

Last Update: 2024-03-27T11:27:40Z Word Count : 10596 Synonim Coronavirus

HBeAg

replication. HBeAg is an antigen that can be found between the icosahedral nucleocapsid core and the lipid envelope (the outer most layer of the hepatitis b...

Last Update: 2023-08-02T07:12:59Z Word Count : 311 Synonim HBeAg

Kennel cough

Transmission electron micrograph of parainfluenza virus. Two intact particles and free filamentous nucleocapsid....

Last Update: 2024-02-02T11:04:51Z Word Count : 1294 Synonim Kennel cough

Zinc finger inhibitor

2008 and some have entered Phase I/II trials as a HIV drug. The HIV-1 nucleocapsid protein 7 (NCp7) is the protein targeted by zinc ejectors. NCp7 is initially...

Last Update: 2021-09-24T13:29:16Z Word Count : 1927 Synonim Zinc finger inhibitor

Adenoviridae

nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. Their name derives from their...

Last Update: 2024-03-08T01:25:35Z Word Count : 5557 Synonim Adenoviridae

Viral tegument

a cluster of proteins that lines the space between the envelope and nucleocapsid of all herpesviruses. The tegument generally contains proteins that aid...

Last Update: 2022-01-10T13:11:51Z Word Count : 375 Synonim Viral tegument

Paramyxoviridae

the envelope stabilise virus structure. The nucleocapsid core is composed of the genomic RNA, nucleocapsid proteins, phosphoproteins and polymerase proteins...

Last Update: 2023-12-03T22:44:17Z Word Count : 2027 Synonim Paramyxoviridae

Nucleoprotein

RNA). Typical nucleoproteins include ribosomes, nucleosomes and viral nucleocapsid proteins. Nucleoproteins tend to be positively charged, facilitating...

Last Update: 2024-03-06T23:55:21Z Word Count : 1964 Synonim Nucleoprotein

HIV

of the viral protein p24. The single-stranded RNA is tightly bound to nucleocapsid proteins, p7, and enzymes needed for the development of the virion such...

Last Update: 2024-03-22T21:55:05Z Word Count : 14345 Synonim HIV

COVID-19

SARS-CoV-2 include membrane glycoprotein (M), envelope protein (E), nucleocapsid protein (N), and the spike protein (S). The M protein of SARS-CoV-2 is...

Last Update: 2024-03-27T23:31:18Z Word Count : 36123 Synonim COVID-19

HBcAg

infectious). HBcAg is an antigen that can be found on the surface of the nucleocapsid core (the inner most layer of the hepatitis B virus). While both HBcAg...

Last Update: 2023-04-25T20:46:05Z Word Count : 308 Synonim HBcAg

Coronaviridae

protein is the phosphoprotein nucleocapsid protein (N), which is responsible for the helical symmetry of the nucleocapsid that encloses the genomic RNA...

Last Update: 2023-12-03T22:06:28Z Word Count : 1285 Synonim Coronaviridae

Herpesviridae

spikes and Nucleocapsid. The four-component Herpes simplex virion encompasses the double-stranded DNA genome into an icosahedral nucleocapsid. There is...

Last Update: 2024-03-28T09:05:11Z Word Count : 2887 Synonim Herpesviridae

SARS-CoV-2

proteins, known as the S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins; the N protein holds the RNA genome, and the S, E, and M proteins...

Last Update: 2024-03-12T21:16:44Z Word Count : 12524 Synonim SARS-CoV-2

Hepatitis B

envelope and an icosahedral nucleocapsid core composed of core protein. These virions are 30–42 nm in diameter. The nucleocapsid encloses the viral DNA and...

Last Update: 2024-03-25T23:18:20Z Word Count : 9293 Synonim Hepatitis B

COVID-19 vaccine

proteins are also being investigated for vaccine development, like the nucleocapsid, because they also induce a robust T-cell response and their genes are...

Last Update: 2024-03-18T08:58:00Z Word Count : 21884 Synonim COVID-19 vaccine

Main result

Capsid

A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The proteins making up the capsid are called capsid proteins or viral coat proteins (VCP). The capsid and inner genome is called the nucleocapsid. Capsids are broadly classified according to their structure. The majority of the viruses have capsids with either helical or icosahedral structure. Some viruses, such as bacteriophages, have developed more complicated structures due to constraints of elasticity and electrostatics. The icosahedral shape, which has 20 equilateral triangular faces, approximates a sphere, while the helical shape resembles the shape of a spring, taking the space of a cylinder but not being a cylinder itself. The capsid faces may consist of one or more proteins. For example, the foot-and-mouth disease virus capsid has faces consisting of three proteins named VP1–3.Some viruses are enveloped, meaning that the capsid is coated with a lipid membrane known as the viral envelope. The envelope is acquired by the capsid from an intracellular membrane in the virus' host; examples include the inner nuclear membrane, the Golgi membrane, and the cell's outer membrane.Once the virus has infected a cell and begins replicating itself, new capsid subunits are synthesized using the protein biosynthesis mechanism of the cell. In some viruses, including those with helical capsids and especially those with RNA genomes, the capsid proteins co-assemble with their genomes. In other viruses, especially more complex viruses with double-stranded DNA genomes, the capsid proteins assemble into empty precursor procapsids that include a specialized portal structure at one vertex. Through this portal, viral DNA is translocated into the capsid.Structural analyses of major capsid protein (MCP) architectures have been used to categorise viruses into lineages. For example, the bacteriophage PRD1, the algal virus Paramecium bursaria Chlorella virus-1 (PBCV-1), mimivirus and the mammalian adenovirus have been placed in the same lineage, whereas tailed, double-stranded DNA bacteriophages (Caudovirales) and herpesvirus belong to a second lineage.


nucleocapsid
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