20 results found for: “ipamorelin”.
Request time (Page generated in 0.3121 seconds.)Growth hormone secretagogue
Last Update: 2023-03-26T05:37:45Z Word Count : 566 Synonim Growth hormone secretagogueUltimate Fighting Championship
Last Update: 2024-04-18T22:04:39Z Word Count : 31401 Synonim Ultimate Fighting ChampionshipGrowth hormone therapy
Last Update: 2024-02-22T14:22:14Z Word Count : 4777 Synonim Growth hormone therapyList of designer drugs
Last Update: 2024-04-17T16:38:52Z Word Count : 8029 Synonim List of designer drugs
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Ipamorelin
Ipamorelin (INN) (developmental code name NNC 26-0161) is a peptide selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue. It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1.Ipamorelin significantly increases plasma growth hormone (GH) levels in both animals and humans. In addition, ipamorelin stimulates body weight gain in animals. Like pralmorelin and GHRP-6, ipamorelin does not affect prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), or thyroid-stimulating hormone (TSH) levels. However, unlike pralmorelin (GHRP-2) and GHRP-6, but similarly to growth hormone-releasing hormone (GHRH), ipamorelin does not stimulate the secretion of adrenocorticotropic hormone (ACTH), or cortisol, and is highly selective for inducing the secretion only of GH.Ipamorelin was originally developed by Novo Nordisk, and was investigated in phase II clinical trials by Helsinn Therapeutics for the treatment of postoperative ileus, but was discontinued due to lack of efficacy.Ipamorelin has been used by athletes as a performance enhancing drug.