20 results found for: “gm-csf”.

Request time (Page generated in 0.3198 seconds.)

Granulocyte-macrophage colony-stimulating factor

Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages...

Last Update: 2023-08-30T11:59:12Z Word Count : 1672 Synonim Granulocyte-macrophage colony-stimulating factor

Granulocyte-macrophage colony-stimulating factor receptor

production of white blood cells. In contrast to M-CSF and G-CSF which are lineage specific, GM-CSF and its receptor play a role in earlier stages of development...

Last Update: 2024-01-02T03:34:05Z Word Count : 2780 Synonim Granulocyte-macrophage colony-stimulating factor receptor

Talimogene laherparepvec

translation machinery to replicate, it also uses it to make the cell create GM-CSF. GM-CSF is secreted or released when the cancer cell bursts, attracting dendritic...

Last Update: 2023-11-03T10:33:00Z Word Count : 1860 Synonim Talimogene laherparepvec

Cytokine release syndrome

associated CRS have elevated levels of IL-6, IFN-γ, IL-8 (CXCL8), IL-10, GM-CSF, MIP-1α/β, MCP-1 (CCL2), CXCL9, and CXCL10 (IP-10). The most predictive...

Last Update: 2024-01-16T11:43:48Z Word Count : 2558 Synonim Cytokine release syndrome

Interleukin 3

of the immune system. In conjunction with other β common chain cytokines GM-CSF and IL-5, IL-3 works to regulate the inflammatory response in order to clear...

Last Update: 2024-02-06T20:10:31Z Word Count : 2622 Synonim Interleukin 3

Otilimab

pathways, GM-CSF has been shown to be involved in autoimmune diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA) in which cases GM-CSF levels...

Last Update: 2023-03-22T15:17:52Z Word Count : 722 Synonim Otilimab

Sargramostim

Leukine) is a recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) that functions as an immunostimulator. Sargramostim is primarily used for...

Last Update: 2024-01-22T21:04:13Z Word Count : 876 Synonim Sargramostim

Interleukin 5

Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF), this glycoprotein in its active form is a homodimer. The IL-5 gene is...

Last Update: 2024-03-13T06:37:38Z Word Count : 1478 Synonim Interleukin 5

Macrophage colony-stimulating factor

stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which causes hematopoietic stem cells to differentiate...

Last Update: 2023-12-21T11:11:14Z Word Count : 2101 Synonim Macrophage colony-stimulating factor

CFU-GM

factor (GM-CSF). There is some controversy over which granulocytes derive from CFU-GM. There is little disagreement that neutrophils come from CFU-GM. Some...

Last Update: 2024-02-18T10:47:44Z Word Count : 202 Synonim CFU-GM

Pulmonary alveolar proteinosis

colony stimulating factor (GM-CSF), a critical factor in development of alveolar macrophages. Decreased bioavailability of GM-CSF results in poor alveolar...

Last Update: 2023-12-27T18:30:00Z Word Count : 2251 Synonim Pulmonary alveolar proteinosis

Lenzilumab

(CSF2)/granulocyte-macrophage colony stimulating factor (GM-CSF). Pre-clinical evidence and clinical data implicate GM-CSF as a crucial initiator in the systemic inflammatory...

Last Update: 2024-01-22T17:35:23Z Word Count : 1120 Synonim Lenzilumab

Inflammatory cytokine

interferon gamma (IFNγ), and granulocyte-macrophage colony stimulating factor (GM-CSF) and play an important role in mediating the innate immune response. Inflammatory...

Last Update: 2024-03-25T12:28:05Z Word Count : 2264 Synonim Inflammatory cytokine

Myeloid-derived suppressor cell

colony stimulating factors (e.g. G-CSF and GM-CSF) have long been used in vivo models of MDSC generation. GM-CSF, G-CSF and IL-6 allow the in vitro generation...

Last Update: 2024-02-26T04:12:48Z Word Count : 2632 Synonim Myeloid-derived suppressor cell

COVID-19

elevated IL‑2, IL‑7, IL‑6, granulocyte-macrophage colony-stimulating factor (GMCSF), interferon gamma-induced protein 10 (IP‑10), monocyte chemoattractant...

Last Update: 2024-03-27T23:31:18Z Word Count : 36123 Synonim COVID-19

Haematopoiesis

factors (CSFs), specifically stimulate the production of committed cells. Three CSFs are granulocyte-macrophage CSF (GM-CSF), granulocyte CSF (G-CSF) and...

Last Update: 2024-03-27T09:02:59Z Word Count : 3345 Synonim Haematopoiesis

Growth factor

colony-stimulating factor (M-CSF) Granulocyte colony-stimulating factor (G-CSF) Granulocyte macrophage colony-stimulating factor (GM-CSF) Epidermal growth factor...

Last Update: 2024-03-13T18:06:21Z Word Count : 1131 Synonim Growth factor

Granulocyte colony-stimulating factor

Granulocyte colony-stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow...

Last Update: 2024-02-21T15:10:33Z Word Count : 3223 Synonim Granulocyte colony-stimulating factor

Mavrilimumab

inhibits human granulocyte macrophage colony-stimulating factor receptor (GM-CSF-R). Mavrilimumab was discovered as CAM-3001 by Cambridge Antibody Technology...

Last Update: 2023-12-20T19:22:38Z Word Count : 608 Synonim Mavrilimumab

CSF2RB

the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF". The EMBO...

Last Update: 2022-05-06T21:47:53Z Word Count : 192 Synonim CSF2RB

Main result

Granulocyte-macrophage colony-stimulating factor

Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Unlike granulocyte colony-stimulating factor, which specifically promotes neutrophil proliferation and maturation, GM-CSF affects more cell types, especially macrophages and eosinophils.


gm-csf
Synonim i słownik wyrazów