9 results found for: “dupixent_side_effects”.

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Dupilumab

Dupilumab, sold under the brand name Dupixent, is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema...

Last Update: 2024-01-28T19:52:15Z Word Count : 1813 Synonim Dupilumab

First-in-class medication

lonafarnib capsule". dailymed.nlm.nih.gov. Retrieved 2021-07-01. "DailyMed - DUPIXENT- dupilumab injection, solution". dailymed.nlm.nih.gov. Retrieved 2021-07-01...

Last Update: 2024-02-12T13:15:49Z Word Count : 842 Synonim First-in-class medication

List of human clusters of differentiation

1016/S1470-2045(15)00132-1. PMID 26179200. https://www.regeneron.com/sites/default/files/Dupixent_FPI.pdf[bare URL PDF] http://www.pieris.com/pipeline/respiratory-anemi...

Last Update: 2022-10-14T06:58:01Z Word Count : 467 Synonim List of human clusters of differentiation

Proprietary drug

interchange between one and another to prevent underlying exposure to more side effects and/or suboptimal treatment. It is believed that generic biopharmaceutical...

Last Update: 2024-01-31T03:12:55Z Word Count : 3289 Synonim Proprietary drug

Atopic dermatitis

In 2017, the monoclonal antibody(mAb) dupilumab under the trade name Dupixent was approved to treat moderate-to-severe eczema. In 2021, an additional...

Last Update: 2024-03-14T01:51:31Z Word Count : 8359 Synonim Atopic dermatitis

Sanofi

(Ranolazine), for stable angina, marketed by Gilead Sciences. – Dermatology Dupixent (Dupilumab), for eczema, marketed by Regeneron. Dynabac (Dirithromycin)...

Last Update: 2024-02-28T15:33:06Z Word Count : 8746 Synonim Sanofi

Aspirin-exacerbated respiratory disease

guidelines. Among biologics and aspirin desensitization and therapy, dupilumab (Dupixent) was show to be the most effective across six different patient-important...

Last Update: 2024-03-11T20:00:23Z Word Count : 5530 Synonim Aspirin-exacerbated respiratory disease

List of therapeutic monoclonal antibodies

Petra; Mueller, Tina; Atz, Judith; Chow, Kai Uwe; et al. (2011). "Cytotoxic effects of the trifunctional bispecific antibody FBTA05 in ex-vivo cells of chronic...

Last Update: 2024-03-23T21:07:07Z Word Count : 3958 Synonim List of therapeutic monoclonal antibodies

Monoclonal antibody therapy

concentration of Aβ plaques. Additionally, there are no associated adverse side effects. Phase III clinical trials of Solanezumab brought about significant reduction...

Last Update: 2024-03-04T12:29:20Z Word Count : 4064 Synonim Monoclonal antibody therapy

Main result

Dupilumab

Dupilumab, sold under the brand name Dupixent, is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis.The most common side effects reported by the US Food and Drug Administration (FDA) include injection site reactions, upper respiratory tract infections, joint pain, and herpes viral infections. The most common side effects reported by the European Medicines Agency (EMA) include injection-site reactions (such as redness, swelling including due to fluid build-up, itching and pain), conjunctivitis (redness and discomfort in the eye) including conjunctivitis due to allergy, joint pain, cold sores, and increased blood levels of a type of white blood cell called eosinophils. It was developed by Regeneron Pharmaceuticals and Sanofi Genzyme. It received approval from the US Food and Drug Administration (FDA) for moderate-to-severe atopic dermatitis in 2017, and for asthma in 2018. The FDA considers it to be a first-in-class medication.Dupilumab is the first treatment for eosinophilic esophagitis approved by the U.S. Food and Drug Administration (FDA). Eosinophilic esophagitis is a chronic inflammatory disorder in which eosinophils, a type of white blood cell, are found in the tissue of the esophagus. In adults and adolescents with eosinophilic esophagitis, common symptoms include difficulty swallowing, difficulty eating, and food getting stuck in the esophagus. Dupilumab is a monoclonal antibody that acts to inhibit part of the inflammatory pathway. Dupilumab is the first treatment for prurigo nodularis approved by the FDA. Prurigo nodularis is a rare skin disease that causes hard, itchy lumps (nodules) to form on the skin.


dupixent_side_effects
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