8 results found for: “andexxa”.

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Andexanet alfa

Andexanet alfa, sold under the brand name Andexxa among others, is an antidote for the medications rivaroxaban and apixaban, when reversal of anticoagulation...

Last Update: 2024-03-31T04:30:02Z Word Count : 1177 Synonim Andexanet alfa

Rivaroxaban

the U.S. Food and Drug Administration in May 2018, under the trade name AndexXa. Rivaroxaban inhibits both free and bound Factor Xa in the prothrombinase...

Last Update: 2024-02-10T00:24:01Z Word Count : 2508 Synonim Rivaroxaban

Apixaban

2020. "Andexxa- andexanet alfa injection, powder, lyophilized, for solution". DailyMed. 8 January 2019. Retrieved 23 December 2019. "Andexxa (coagulation...

Last Update: 2024-03-07T02:56:16Z Word Count : 1889 Synonim Apixaban

Alexion Pharmaceuticals

(Kanuma), used to treat lysosomal acid lipase deficiency, and andexanet alfa (Andexxa), used to stop life threatening or uncontrollable bleeding in people who...

Last Update: 2024-03-12T17:48:58Z Word Count : 1377 Synonim Alexion Pharmaceuticals

Portola Pharmaceuticals

case in the proposed settlement amount of $17.5 million. Andexanet alfa (Andexxa), a coagulation factor Xa (recombinant), inactivated-zhzo, the first and...

Last Update: 2024-02-27T19:42:04Z Word Count : 634 Synonim Portola Pharmaceuticals

Edoxaban

2019. Ovanesov M (3 August 2017). "Summary basis for regulatory action - ANDEXXA". Food and Drug Administration. Retrieved 6 November 2019. "Ondexxya"....

Last Update: 2024-04-07T05:23:24Z Word Count : 1035 Synonim Edoxaban

Direct factor Xa inhibitors

Portola Pharmaceuticals, Inc. "U.S. FDA Approves Portola Pharmaceuticals' Andexxa, First and Only Antidote for the Reversal of Factor Xa Inhibitors". GlobeNewswire...

Last Update: 2024-02-03T03:57:41Z Word Count : 1525 Synonim Direct factor Xa inhibitors

Discovery and development of direct Xa inhibitors

clinical trials. These are letaxaban from Takeda and eribaxaban from Pfizer. Andexxa (Andexanet alfa) from Portola Pharmaceuticals is a recombinant protein...

Last Update: 2023-11-23T19:20:28Z Word Count : 4916 Synonim Discovery and development of direct Xa inhibitors

Main result

Andexanet alfa

Andexanet alfa, sold under the brand name Andexxa among others, is an antidote for the medications rivaroxaban and apixaban, when reversal of anticoagulation is needed due to uncontrolled bleeding. It has not been found to be useful for other factor Xa inhibitors. It is given by injection into a vein.Common side effects include pneumonia and urinary tract infections. Severe side effects may include blood clots, heart attacks, strokes, or cardiac arrest. It works by binding to rivaroxaban and apixaban.It was approved for medical use in the United States in May 2018. It was developed by Portola Pharmaceuticals.