Vinpocetine

Vinpocetine
Clinical data
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • Not recommended[1]
Routes of
administration
Oral, intravenous
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability56.6 ± 8.9%
Metabolismhepatic
Elimination half-life2.54 ± 0.48 hours
Excretionrenal
Identifiers
  • (3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.050.917 Edit this at Wikidata
Chemical and physical data
FormulaC22H26N2O2
Molar mass350.462 g·mol−1
3D model (JSmol)
  • O=C(OCC)C=4n1c3c(c2ccccc12)CCN5[C@H]3[C@](C=4)(CCC5)CC
  • InChI=1S/C22H26N2O2/c1-3-22-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(19(16)20(22)23)18(14-22)21(25)26-4-2/h5-6,8-9,14,20H,3-4,7,10-13H2,1-2H3/t20-,22+/m1/s1 checkY
  • Key:DDNCQMVWWZOMLN-IRLDBZIGSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Vinpocetine (ethyl apovincaminate) is a synthetic derivative of the vinca alkaloid vincamine, differing by the removal of a hydroxyl group and by being the ethyl rather than the methyl ester of the underlying carboxylic acid. Vincamine is extracted from either the seeds of Voacanga africana or the leaves of Vinca minor (lesser periwinkle).

  1. ^ Cite error: The named reference FDA2019Preg was invoked but never defined (see the help page).
  2. ^ "Vinpocetine in Dietary Supplements". FDA. February 22, 2023. Retrieved June 9, 2023.