20 results found for: “bone_resorption”.

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Bone resorption

Bone resorption is resorption of bone tissue, that is, the process by which osteoclasts break down the tissue in bones and release the minerals, resulting...

Last Update: 2023-10-31T23:56:54Z Word Count : 2218 Synonim Bone resorption

Resorption

Resorption is the absorption of cells or tissue into the circulatory system, usually by osteoclasts. Types of resorption include: Bone resorption Herniated...

Last Update: 2023-12-03T17:28:09Z Word Count : 110 Synonim Resorption

Bone remodeling

osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and...

Last Update: 2023-12-03T19:09:17Z Word Count : 521 Synonim Bone remodeling

Osteocyte

destroyed, the bones showed a significant increase in bone resorption, decreased bone formation, trabecular bone loss, and loss of response to unloading. Osteocytes...

Last Update: 2023-09-20T19:16:15Z Word Count : 2520 Synonim Osteocyte

Osteoporosis

imbalance between bone resorption and bone formation. In normal bone, matrix remodeling of bone is constant; up to 10% of all bone mass may be undergoing...

Last Update: 2024-02-06T20:35:29Z Word Count : 13415 Synonim Osteoporosis

Tooth resorption

primary dentition. While resorption of bone is a normal physiological response to stimuli throughout the body, root resorption in permanent dentition and...

Last Update: 2023-08-13T10:27:17Z Word Count : 1818 Synonim Tooth resorption

Bone

involved in the formation and mineralisation of bone; osteoclasts are involved in the resorption of bone tissue. Modified (flattened) osteoblasts become...

Last Update: 2024-03-21T12:24:53Z Word Count : 8827 Synonim Bone

Osteolysis

Osteolysis is an active resorption of bone matrix by osteoclasts and can be interpreted as the reverse of ossification. Although osteoclasts are active...

Last Update: 2023-11-18T16:47:15Z Word Count : 430 Synonim Osteolysis

Osteoclast

process known as bone resorption. This process also helps regulate the level of blood calcium. Osteoclasts are found on those surfaces of bone that are undergoing...

Last Update: 2024-03-25T01:53:04Z Word Count : 2925 Synonim Osteoclast

Condylar resorption

which one or both of the mandibular condyles are broken down in a bone resorption process. This disorder is nine times more likely to be present in females...

Last Update: 2023-12-03T07:34:33Z Word Count : 495 Synonim Condylar resorption

Hypercalcaemia

new bone) via the rank ligand pathway leading to bone resorption and calcium release into the bloodstream. The massive release of calcium from bone metastasis...

Last Update: 2024-03-27T03:10:37Z Word Count : 3298 Synonim Hypercalcaemia

C-terminal telopeptide

specific to bone resorption than any other test currently available. In the early 2000s, a link between bisphosphonate use and impaired bone physiology...

Last Update: 2024-01-02T07:29:39Z Word Count : 755 Synonim C-terminal telopeptide

Idiopathic hypercalcinuria

that IH patients had lower bone density, suggesting increased bone resorption. Bone resorption involves the breaking down of bone tissue and the transfer...

Last Update: 2023-12-31T19:44:40Z Word Count : 3175 Synonim Idiopathic hypercalcinuria

Hyperparathyroidism

(hypercalcemia) due to:[citation needed] increased bone resorption, allowing the flow of calcium from bone to blood reduced kidney clearance of calcium increased...

Last Update: 2024-03-18T05:08:11Z Word Count : 5232 Synonim Hyperparathyroidism

Artificial bone

Human bones have the ability to regenerate themselves by cycle of bone resorption and bone formation. The cell responsible for bone resorption is osteoclast...

Last Update: 2023-11-29T03:28:55Z Word Count : 2867 Synonim Artificial bone

Osteopetrosis

and bone resorption by osteoclasts is defective, as an acidic environment is needed to dissociate calcium hydroxyapatite from the bone matrix. As bone resorption...

Last Update: 2024-03-18T09:45:14Z Word Count : 2736 Synonim Osteopetrosis

Osteoprotegerin

Osteoporosis is a bone-related disease caused by increased rates of bone resorption compared to bone formation. A higher rate of resorption is often caused...

Last Update: 2023-12-11T09:12:11Z Word Count : 3686 Synonim Osteoprotegerin

Calcitonin

therefore not directly affected by calcitonin levels. However, since bone resorption and bone formation are coupled processes, eventually calcitonin's inhibition...

Last Update: 2024-03-10T02:04:35Z Word Count : 3097 Synonim Calcitonin

Osteitis fibrosa cystica

activity of osteoclasts, cells that break down bone, in a process known as osteoclastic bone resorption. The hyperparathyroidism can be triggered by a...

Last Update: 2024-01-19T15:10:49Z Word Count : 4028 Synonim Osteitis fibrosa cystica

Bone healing

osteoblasts, which form woven bone[citation needed] through bone resorption of calcified cartilage and recruitment of bone cells and osteoclasts. The fibroblasts...

Last Update: 2023-12-25T02:45:07Z Word Count : 2052 Synonim Bone healing

Main result

Bone resorption

Bone resorption is resorption of bone tissue, that is, the process by which osteoclasts break down the tissue in bones and release the minerals, resulting in a transfer of calcium from bone tissue to the blood.The osteoclasts are multi-nucleated cells that contain numerous mitochondria and lysosomes. These are the cells responsible for the resorption of bone. Osteoblasts are generally present on the outer layer of bone, just beneath the periosteum. Attachment of the osteoclast to the osteon begins the process. The osteoclast then induces an infolding of its cell membrane and secretes collagenase and other enzymes important in the resorption process. High levels of calcium, magnesium, phosphate and products of collagen will be released into the extracellular fluid as the osteoclasts tunnel into the mineralized bone. Osteoclasts are prominent in the tissue destruction found in psoriatic arthritis and rheumatological disorders.The human body is in a constant state of bone remodeling. Bone remodeling is a process which maintains bone strength and ion homeostasis by replacing discrete parts of old bone with newly synthesized packets of proteinaceous matrix. Bone is resorbed by osteoclasts, and is deposited by osteoblasts in a process called ossification. Osteocyte activity plays a key role in this process. Conditions that result in a decrease in bone mass can either be caused by an increase in resorption or by a decrease in ossification. During childhood, bone formation exceeds resorption. As the aging process occurs, resorption exceeds formation.Bone resorption rates are much higher in post-menopausal older women due to estrogen deficiency related with menopause. Common treatments include drugs that increase bone mineral density. Bisphosphonates, RANKL inhibitors, SERMs—selective oestrogen receptor modulators, hormone replacement therapy and calcitonin are some of the common treatments. Light weight bearing exercise tends to eliminate the negative effects of bone resorption.


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