Muscarinic acetylcholine receptor M2

CHRM2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCHRM2, HM2, cholinergic receptor muscarinic 2
External IDsOMIM: 118493 MGI: 88397 HomoloGene: 20190 GeneCards: CHRM2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_203491

RefSeq (protein)

NP_987076

Location (UCSC)Chr 7: 136.87 – 137.02 MbChr 6: 36.37 – 36.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene.[5] Multiple alternatively spliced transcript variants have been described for this gene.[5] It is Gi-coupled, reducing intracellular levels of cAMP.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181072 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045613 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: CHRM2 cholinergic receptor, muscarinic 2".