|Trade names||Amikin, Amiglyde-V, Arikayce, others|
|Elimination half-life||2–3 hours|
|CompTox Dashboard (EPA)|
|Chemical and physical data|
|Molar mass||585.608 g·mol−1|
|3D model (JSmol)|
Amikacin is an antibiotic medication used for a number of bacterial infections. This includes joint infections, intra-abdominal infections, meningitis, pneumonia, sepsis, and urinary tract infections. It is also used for the treatment of multidrug-resistant tuberculosis. It is used by injection into a vein using an IV or into a muscle.
Amikacin, like other aminoglycoside antibiotics, can cause hearing loss, balance problems, and kidney problems. Other side effects include paralysis, resulting in the inability to breathe. If used during pregnancy it may cause permanent deafness in the baby. Amikacin works by blocking the function of the bacteria's 30S ribosomal subunit, making it unable to produce proteins.
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